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FRANCHISE RESALES

Buy a Prime IV Hydration Franchise

Prime IV Hydration & Wellness is a health and wellness franchise specializing in IV therapy, vitamin injections, and personalized wellness consultations. Founded in 2017 and franchising since 2020, the brand delivers proprietary IV nutrient blends directly into the bloodstream for rapid absorption, with locations operating across 42 states.

Each Prime IV location is built around a spa-format environment, featuring zero-gravity massage chairs and on-site sterile compounding rooms, with every session led by medically trained clinical staff. Services span hydration, recovery, anti-aging, immunity, and weight management, complemented by vitamin injection add-ons and membership plans that build a recurring customer base.

The franchisee’s role is operational oversight rather than clinical delivery. Owners manage a small team, typically two or more trained employees who handle day-to-day treatments. The model is designed to support semi-absentee ownership once a location is established, with protected territories and a membership-driven revenue component providing ongoing client retention.

Latest Resales

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Why buy a Prime IV Hydration Franchise?

The IV wellness category has continued to grow as consumers seek convenient, clinic-quality treatments for recovery, immunity, and energy. Prime IV’s membership model converts one-time clients into recurring visitors, building a more predictable revenue base than session-by-session wellness formats. The brand’s proprietary IV blends, spa-format environment, and medical supervision distinguish it from independent operators.

Prime IV’s national recognition in Entrepreneur’s Franchise 500 and multiple Franchise Business Review categories signals a system with established credibility. The small staffing model, with clinical operations run by two or more trained employees, keeps overhead manageable relative to larger health services formats. Semi-absentee ownership is supported once a unit is operating, broadening the buyer profile.

Prime IV Hydration Franchise Costs & Information

Based on 2025 data reported in the 2026 FDD

  • Brand Profile

    • Year Founded

      2019

    • Franchising Since

      2020

    • New Startup Cost

      $187,701 – $606,693

    • Avg. Resale Price

      Contact us for details

  • Franchise Fees

    • Initial franchise Fee

      $49,000

      for new territories

    • Transfer Fee

      30%

      of the then-existing Initial Franchise Fee

    • Royalty Fee

      7%

      of Gross Revenues

    • Marketing Fee

      1%

      of Gross Revenues

  • Unit Performance

    • Total Units *

      212

    • New Units Opened *

      60

    • Units Transferred *

      9

    • Avg. Unit revenue *

      $492,568

    * Based on 2025 data reported in the 2026 FDD

Prime IV Hydration – Additional  Information

  1. Training & Support

    Prime IV provides initial training covering 28 hours of classroom instruction and 17 hours of on-the-job training, led by medical professionals and covering both operational and clinical protocols. Ongoing support includes proprietary social media marketing systems, operational guidance, and access to established supplier relationships. All locations are required to follow USP 797 compounding safety standards. Resale buyers should confirm with Prime IV what onboarding and initial training is available to incoming ownership and what system and clinical protocol access carries over with the transfer.

  2. Ideal Owner

    Prime IV suits owners comfortable overseeing a small clinical team in a customer-facing wellness environment, without requiring a medical background themselves. Day-to-day service delivery is handled by medically trained staff, so the owner's key skills are in staff management, local marketing, and customer experience rather than clinical practice. The model appeals to semi-absentee buyers with prior management or business experience, as well as health-and-wellness-oriented operators who want a community-facing concept with recurring membership revenue.

  3. Recognition & Awards

    Prime IV Hydration & Wellness has earned recognition across multiple franchise rankings. The brand ranked #72 in Entrepreneur's Franchise 500 in 2026 and has placed #1 in the IV Therapy category in the 2024, 2025, and 2026 Franchise 500 listings. Franchise Business Review has recognised Prime IV as a Top 200 Franchise (2025 and 2026), Top Franchise for Women (2025 and 2026), Top Franchise for Veterans (2025), Top Culture (2025 and 2026), and Most Innovative Franchise (2024). The brand also appears on the Inc. 5000 list and is a VetFran member.

  4. Industry / Market

    The US IV hydration therapy market was valued at approximately $1.11 billion in 2024 and is projected to reach around $2.43 billion by 2034 (Precedence Research), driven by growing consumer interest in preventive wellness and convenient alternatives to traditional clinical care. The North American market reflects a similar upward trajectory. Demand spans athletes, working professionals, and health-conscious adults seeking energy, immunity, and recovery support. For resale buyers, local market depth and the strength of an existing membership base are important factors when evaluating a specific unit.

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